منابع مشابه
Second consensus statement on the diagnosis of multiple system atrophy.
BACKGROUND A consensus conference on multiple system atrophy (MSA) in 1998 established criteria for diagnosis that have been accepted widely. Since then, clinical, laboratory, neuropathologic, and imaging studies have advanced the field, requiring a fresh evaluation of diagnostic criteria. We held a second consensus conference in 2007 and present the results here. METHODS Experts in the clini...
متن کاملDiagnosis and Treatment of Multiple System Atrophy: an Update
This review provides an update on the diagnosis and therapy of multiple system atrophy (MSA), a sporadic neurodegenerative disorder characterised clinically by any combination of parkinsonian, autonomic, cerebellar or pyramidal symptoms and signs and pathologically by cell loss, gliosis and glial cytoplasmic inclusions in several brain and spinal cord structures. The term MSA was introduced in ...
متن کاملMultiple system atrophy.
Multiple system atrophy (MSA) is an adult-onset sporadic progressive neurodegenerative disorder of unknown etiology. It is clinically characterized by the variable combination of autonomic failure, parkinsonism, cerebellar ataxia, and pyramidal signs. The present review summarizes up-to-date knowledge on the clinical diagnosis and molecular pathology of MSA. We also review the role of additiona...
متن کاملMultiple system atrophy.
Multiple system atrophy is a neurological disorder that has gone unrecognized for too long due to its involvement across multiple regions of the central nervous system. This disorder is finally being unveiled through increased reporting in the scientific literature. Further research will enhance our understanding of this disease and lead to more effective treatment regimens as well as an improv...
متن کاملMultiple system atrophy.
Although the precise definition of multiple system atrophy has been difficult, a recent consensus in diagnostic criteria for multiple system atrophy has been achieved. This should lead to progress in defining the underlying pathophysiology of the neuroendocrine, autonomic and motor deficits characteristic of multiple system atrophy. Hopefully, these developments will lead to effective treatment.
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ژورنال
عنوان ژورنال: Autonomic Neuroscience
سال: 2018
ISSN: 1566-0702
DOI: 10.1016/j.autneu.2017.10.007